Abnova™ Human MAPK8 (NM_002750.2, 1 a.a.- 384 a.a.) Full-length Recombinant Protein

Catalog No.	Quantity
89-951-762	100 μg

Catalog No. 89-951-762 Supplier Abnova™ Supplier No. P4710

Description

Used for Func, SDS-PAGE

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

• Accession Number: NM_002750.2
• Concentration: 0.513 ug/uL
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 5599
• Molecular Weight (g/mol): 44.292kDa
• Name: MAPK8 (Human) Recombinant Protein
• Preparation Method: Escherichia coli expression system
• Purification Method: Immobilized metal affinity chromatography
• Quality Control Testing: 2 ug/lane SDS-PAGE Stained with Coomassie Blue
• Quantity: 100 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing
• Regulatory Status: RUO
• Gene Alias: JNK/JNK1/JNK1A2/JNK21B1/2/PRKM8/SAPK1
• Common Name: MAPK8
• Gene Symbol: MAPK8
• Biological Activity: 2514pmol/μg x min
• Species: E. coli
• Recombinant: Recombinant
• Protein Tag: None
• Expression System: Escherichia coli expression system
• Form: Liquid