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Abnova™ Human MIF (AAA36315) Recombinant Protein

Catalog No. 89952503 Shop All Abnova Corporation Products
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25 μg
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89-952-503 25 μg
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Catalog No. 89-952-503 Supplier Abnova™ Supplier No. P4426
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Used for Func, SDS-PAGE

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq]

Sequence: MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA

Specifications

Accession Number AAA36315
For Use With (Application) Functional Study, SDS-PAGE
Formulation Lyophilized
Gene ID (Entrez) 4282
Molecular Weight (g/mol) 12.5kDa
Name MIF (Human) Recombinant Protein
Preparation Method Escherichia coli expression system
Quality Control Testing 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue
Quantity 25 μg
Immunogen MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
Storage Requirements Store at -20°C on dry atmosphere. After reconstitution with sterilized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Endotoxin Concentration <0.1 EU/μg
Gene Alias GIF/GLIF/MMIF
Common Name MIF
Gene Symbol MIF
Biological Activity The activity is determined by an agarose microdroplet assay using human U937 cells as targets and is 0.5-1μg/mL and the production of IL-8 by human PBMCs. The expected ED50 for this effect is 88-132ng/mL.
Species E. coli
Recombinant Recombinant
Protein Tag None
Expression System Escherichia coli expression system
Form Lyophilized
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