Gibco™ Human MIP-3 (CCL23) Recombinant Protein, PeproTech®

Catalog No.	Quantity
30029250UG	250 μg
30029100UG	100 μg
300-29-1MG	1 mg
300-29-20UG	20 μg
30029500UG	500 μg
300-29-5UG	5 μg

Catalog No. 30029250UG Supplier Gibco™ Supplier No. 30029250UG

Description

Recombinant Protein

Recombinant Human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

Specifications

• Accession Number: P55773
• For Use With (Application): ELISA, Functional Assay, Western Blot
• Formulation: protein with no preservative
• Gene ID (Entrez): 6368
• Molecular Weight (g/mol): 11.3 kDa
• Name: Human MIP-3 (CCL23)
• Quantity: 250 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: C6 beta-chemokine; C-C motif chemokine 23; C-C motif chemokine ligand 23; CCL23; CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99); chemokine (C-C motif) ligand 23; Ck beta 8-1; CKb8; CKB-8; Ckb-8-1; CK-BETA-8; hmrp-2 A; Macrophage inflammatory protein 3; MIP3; MIP-3; MIP-3 CK-BETA-8; MPIF1; MPIF-1; MPIF-1 Ckb-8-1; Myeloid progenitor inhibitory factor 1; SCYA23; small inducible cytokine subfamily A (Cys-Cys), member 23; Small-inducible cytokine A23
• Common Name: CCL23
• Gene Symbol: CCL23
• Biological Activity: Determined by its ability to chemoattract human T cell population using a concentration of 10-50 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.