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Gibco™ Human Myostatin Propeptide Recombinant Protein, PeproTech®

Catalog No. 120125UG
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Catalog No. Quantity
120-12-5UG 5 μg
12012100UG 100 μg
120-12-1MG 1 mg
12012250UG 250 μg
120-12-25UG 25 μg
12012500UG 500 μg
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Description

Recombinant Protein

Recombinant Human Myostatin-Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Mature myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin-Propeptide exhibits high binding affinity for myostatin, and has been shown to be a potent inhibitor of myostatin. Over-expression of myostatin-propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in myostatin knockout mice.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O14793
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 2660
Molecular Weight (g/mol) 27.8 kDa
Name Human Myostatin Propeptide
Quantity 5 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias Myostatin
Common Name pro-Myostatin
Gene Symbol MSTN
Biological Activity Determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.01-0.04 ug/ml in the presence of 50 ng/ml Myostatin.
Conjugate Unconjugated
Recombinant Recombinant
Sequence MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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