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Gibco™ Human NNT-1/BCSF-3 Recombinant Protein, PeproTech®

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Description
Recombinant Human NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
NNT-1/BCSF-3 is a neurotrophic factor with B-cell-stimulating capabilities. Expressed in the lymph nodes and spleen, NNT-1/BCSF-3 activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member b (LIFR-b) by binding and inducing the tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss, and B cell hyperplasia associated with increases in serum IgG and IgM.

Specifications
Specifications
Accession Number | Q9UBD9 |
For Use With (Application) | ELISA, Functional Assay, Western Blot |
Formulation | protein with no preservative |
Gene ID (Entrez) | 23529 |
Molecular Weight (g/mol) | 22.4 kDa |
Name | Human NNT-1/BCSF-3 |
Quantity | 100 μg |
Source | E. coli |
Regulatory Status | RUO |
Endotoxin Concentration | <1 EU/ μg |
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