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Gibco™ Human NNT-1/BCSF-3 Recombinant Protein, PeproTech®
SDP

E. coli Recombinant Protein

Supplier:  Gibco™ 4501810UG

Encompass

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Catalog No. 450-18-10UG


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Description

Description

NNT-1/BCSF-3 is a neurotrophic factor with B-cell-stimulating capabilities. Expressed in the lymph nodes and spleen, NNT-1/BCSF-3 activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member b (LIFR-b) by binding and inducing the tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss, and B cell hyperplasia associated with increases in serum IgG and IgM.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Q9UBD9
protein with no preservative
22.4
10 μg
-20°C
<1 EU/μg
CLCF1
Unconjugated
MLNRTGDPGP GPSIQKTYDL TRYLEHQLRS LAGTYLNYLG PPFNEPDFNP PRLGAETLPR ATVDLEVWRS LNDKLRLTQN YEAYSHLLCY LRGLNRQAAT AELRRSLAHF CTSLQGLLGS IAGVMAALGY PLPQPLPGTE PTWTPGPAHS DFLQKMDDFW LLKELQTWLW RSAKDFNRLK KKMQPPAAAV TLHLGAHGF
≥ 98% by SDS-PAGE gel and HPLC analyses.
ELISA, Functional Assay, Western Blot
23529
Human NNT-1/BCSF-3
E. coli
RUO
b cell-stimulating factor 3; B-cell stimulating factor 3; B-cell stimulatory factor 3; B-cell-stimulating factor 3; Bsf3; BSF-3; Cardiotrophin-like cytokine factor 1; CISS2; Clc; CLCF1; CRLF1 associated cytokine-like factor 1; neurotrophin-1/B-cell stimulating factor-3; NNT1; NNT-1; NNT-1/BSF-3; Novel neurotrophin-1; NR6
Human
Recombinant
Lyophilized
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