Gibco™ Human NT-4 Recombinant Protein

Catalog No.	Quantity
PHC7024	10 μg

Catalog No. PHC7024 Supplier Gibco™ Supplier No. PHC7024

Description

Recombinant Protein

Carrier-Free Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute rhNT-4 in sterile distilled water at a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C. Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles.

This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.

Specifications

• Accession Number: P34130
• For Use With (Application): Bioactivity
• Formulation: Protein with no preservative
• Gene ID (Entrez): 4909
• Molecular Weight (g/mol): 27.2 kDa
• Name: Human NT-4
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -20°C
• Regulatory Status: RUO
• Endotoxin Concentration: <0.1 ng/μg
• Gene Alias: 2900040K06Rik; AI462899; GLC10; GLC1O; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 4; Neurotrophin 4/5; neurotrophin 5; Neurotrophin 5 (neurotrophin 4/5); neurotrophin 5 (neurotrophin 4/5); neurotrophin-4; Neurotrophin-5; neutrophic factor 4; Neutrophic factor 5; NT4; NT-4; NT4/5; NT-4/5; NT4/NT5; NT4P; NT5; NT-5; Ntf4; Ntf5; Ntf-5
• Common Name: NTF4
• Gene Symbol: NTF4
• Biological Activity: ED50 = 20 - 50 ng/mL; determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain septal cultures.
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: Human NT-4 recombinant protein is a homodimer containing two 130 amino acid subunits
• Content And Storage: -20°C
• Classification: Carrier-Free
• Activity: ED50 = 20 - 50 ng/mL; determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain septal cultures.
• Endotoxin Level: <0.1 ng/μg
• Shipping Condition: Approved for shipment on Wet or Dry Ice
• Expression System: E. coli
• Protein Family: Growth Factors & Receptors
• Protein Form: Recombinant, Ligand
• Form: Lyophilized
• Protein Subtype: Neurotrophic Factors
• Research Category: Neurobiology, Stem Cell Research, Differentiation, Signal Transduction
• Product Line: Gibco
• Purity or Quality Grade: ≥98% by SDS-PAGE and HPLC