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Invitrogen™ Human NUMB Synthetic Peptide

Catalog No. PEP1257
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50 μg
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Catalog No. Quantity
PEP1257 50 μg
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Catalog No. PEP1257 Supplier Invitrogen™ Supplier No. PEP1257
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Description

Synthetic Peptide

NUMB Synthetic Peptide, PEP-1257, from Invitrogen.

Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 8650
Species Human
Purification Method purified
Accession Number P49757
Common Name Human NUMB
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol NUMB
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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