Gibco™ Human Oncostatin M (209 aa) Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Supplier:  Gibco™ 30010T100UG

Catalog No. 30010T100UG

Description

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.

Specifications

• Accession Number: P13725
• Format: Lyophilized
• Gene ID (Entrez): 5008
• Name: Human Oncostatin M (209 aa)
• Quantity: 100 µg
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/µg
• Gene Symbol: OSM
• Conjugate: Unlabeled
• Sequence: AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRR

• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 23.6
• Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: MGC20461; OncoM; oncostatin M; oncostatin-M; OSM
• Specific Reactivity: Human
• Recombinant: Yes