Abnova™ Human PAK2 kinase domain (Q13177, 227 a.a. - 524 a.a.) Partial Recombinant Protein

Description

Used for Func, SDS-PAGE

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq]

Specifications

• Accession Number: Q13177
• Concentration: 1 mg/ml
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 5062
• Molecular Weight (g/mol): 33.5kDa
• Name: PAK2 (Human) Recombinant Protein
• Preparation Method: Escherichia coli expression system
• Quality Control Testing: Loading 6 ug protein in SDS-PAGE
• Quantity: 10 μg
• Immunogen: GPHMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR The first 4 residues GPHM are from Turbo3C Protease cleavage site. The underlined T is phosphorylated T402.
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: PAK65/PAKgamma
• Common Name: PAK2
• Gene Symbol: PAK2
• Biological Activity: Specific activity: 85,806pmoles/min/μg
• Species: E. coli
• Recombinant: Recombinant
• Protein Tag: None
• Expression System: Escherichia coli expression system
• Form: Liquid