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R&D Systems™ Human PCSK9 (NP_777596) VersaClone cDNA

Catalog No. RDC2709
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RDC2709 10 μg
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Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

  • Also known as: FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3
  • PCSK9 is a member of the subtilisinlike proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway.
  • It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation.
  • It plays a role in cholesterol and fatty acid metabolism.
  • Mutations in PCSK9 have been associated with autosomal dominant familial hypercholesterolemia.
  • Alternatively spliced transcripts encoding different proteins have been described.
  • The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
  • For reasearch use only. Not for use in humans.

Specifications

Gene Proprotein Convertase 9/PCSK9
Accession Number NP_777596
Concentration 10 μg at 0.2 μg/μL
Formulation cDNA is provided in 10 mM Tris-Cl, pH 8.5
Insert Type 2092 bp
Gene ID (Entrez) 255738
Gene Alias EC 3.4.21, EC 3.4.21.111, FH3, FH3neural apoptosis regulated convertase 1, FHCL3, HCHOLA3, hypercholesterolemia, autosomal dominant 3, LDLCQ1, NARC1, NARC-1, NARC-1 convertase subtilisin/kexin type 9 preproprotein, NARC1EC 3.4.21.-, Neural apoptosis-regulated convertase 1, PC9, PCSK9, Proprotein convertase 9, proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9
Content And Storage Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species Human
Quantity 10 μg
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