Invitrogen™ Human PD-L1 Synthetic Peptide

Catalog No.	Quantity
PEP0463	50 μg

Catalog No. PEP0463 Supplier Invitrogen™ Supplier No. PEP0463

Description

Synthetic Peptide

PDL-1 Synthetic Peptide, PEP-0463, from Invitrogen.

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.

Specifications

• Gene ID (Entrez): 29126
• Species: Human
• Purification Method: purified
• Accession Number: Q9NZQ7
• Common Name: Human PD-L1
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: CD274
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS