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  4. Abnova™ Human PIK3C2A Partial ORF (NP_002636, 1577 a.a. - 1686 a.a.) Recombinant Protein with GST-tag at N-terminal

Abnova™ Human PIK3C2A Partial ORF (NP_002636, 1577 a.a. - 1686 a.a.) Recombinant Protein with GST-tag at N-terminal

Catalog No. 89956943 Shop All Abnova Corporation Products
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89-956-943 25 ug
89-956-942 10 ug
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Catalog No. 89-956-943 Supplier Abnova™ Supplier No. H00005286Q01L

Description

Used for AP, Array, ELISA, WB-Re

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq]

Sequence: MVMHIKDLVTEDGADPNPYVKTYLLPDNHKTSKRKTKISRKTRNPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPLKDFNLSKETVKWYQLTAATYL

Specifications

Accession Number NP_002636
For Use With (Application) Antibody Production, ELISA, Protein Array, Western Blot
Formulation 50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene ID (Entrez) 5286
Molecular Weight (g/mol) 37.84kDa
Name PIK3C2A (Human) Recombinant Protein (Q01)
Quality Control Testing 12.5% SDS-PAGE Stained with Coomassie Blue.
Quantity 25 ug
Immunogen MVMHIKDLVTEDGADPNPYVKTYLLPDNHKTSKRKTKISRKTRNPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPLKDFNLSKETVKWYQLTAATYL
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Gene Alias CPK/DKFZp686L193/MGC142218/PI3-K-C2(ALPHA)/PI3-K-C2A
Common Name PIK3C2A
Gene Symbol PIK3C2A
Species Wheat Germ (in vitro)
Recombinant Recombinant
Protein Tag GST
Expression System wheat germ expression system
Form Liquid
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