Gibco™ Human PlGF-2 Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human PlGF-2 is a 34.6 kDa disulfide-linked homodimeric protein of two 152 amino acid polypeptide chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

PlGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-2 is expressed in umbilical vein endothelial cells and placenta. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. PlGF-2 also signals through Neuropilin (NP-1), and can bind with high affinity to heparin.

Specifications

• Accession Number: P49763
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 5228
• Molecular Weight (g/mol): 34.6 kDa
• Name: Human PlGF-2
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Common Name: PlGF-2
• Gene Symbol: PGF
• Biological Activity: Determined by its ability to chemoattract human THP-1 cells of using a concentration range of 5.0-50.0 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.