Invitrogen™ Human PON2 Recombinant Protein

Catalog No.	Quantity
PIRP75681	1 mg

Catalog No. PIRP75681 Supplier Invitrogen™ Supplier No. RP75681

Description

Recombinant Protein

This product contains purified recombinant human Paraoxonase 2 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Accession Number: Q15165
• Concentration: 0.10 mg/mL
• For Use With (Application): Control, Western Blot
• Formulation: 20 mM tris HCl with 50% glycerol and no preservative; pH 8
• Gene ID (Entrez): 5445
• Name: Human PON2
• pH Range: 8
• Quantity: 1 mg
• Source: E. coli
• Immunogen: N/A
• Regulatory Status: RUO
• Gene Alias: 6330405I24Rik; A esterase 2; A-esterase 2; AI481612; aromatic esterase 2; arylesterase 2; paraoxonase 2; paraoxonase nirs; PON 2; PON2; Serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2
• Common Name: PON2
• Gene Symbol: PON2
• Conjugate: Unconjugated
• Species: E. coli
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Amino acids Met1- Leu354 containing an N-terminal His-tag
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Protein Subtype: Recombinant
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions