Abnova™ Human PRKCG (NM_002739.3, 1 a.a. - 697 a.a.) Full-length Recombinant Protein with GST-His tag expressed in Sf9 cells

Catalog No.	Quantity
89-958-179	100 μg

Catalog No. 89-958-179 Supplier Abnova™ Supplier No. P4759

Description

Used for Func, SDS-PAGE

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq]

Specifications

• Accession Number: NM_002739.3
• Concentration: 0.088 ug/uL
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 5582
• Molecular Weight (g/mol): 112.289kDa
• Name: PRKCG (Human) Recombinant Protein
• Preparation Method: Insect cell (Sf9) expression system
• Purification Method: One-step affinity purification using GSH agarose
• Quality Control Testing: 2 ug/lane SDS-PAGE Stained with Coomassie Blue
• Quantity: 100 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing
• Regulatory Status: RUO
• Gene Alias: MGC57564/PKC-gamma/PKCC/PKCG/SCA14
• Common Name: PRKCG
• Gene Symbol: PRKCG
• Biological Activity: 325pmol/μg x min
• Species: Baculovirus
• Recombinant: Recombinant
• Protein Tag: GST-His
• Expression System: Insect cell (Sf9) expression system
• Form: Liquid