Abnova™ Human PRKCH (P24723) Full-length Recombinant Protein with GST expressed in Sf9 cells

Catalog No.	Quantity
89-958-181	5 μg

Catalog No. 89-958-181 Supplier Abnova™ Supplier No. P4215

Description

Used for Func, SDS-PAGE

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. [provided by RefSeq]

Specifications

• Accession Number: P24723
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 5583
• Molecular Weight (g/mol): 103kDa
• Name: PRKCH (Human) Recombinant Protein
• Quality Control Testing: 1 ug/lane SDS-PAGE Stained with Coomassie Blue
• Quantity: 5 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: MGC26269/MGC5363/PKC-L/PKCL/PRKCL/nPKC-eta
• Common Name: PRKCH
• Gene Symbol: PRKCH
• Biological Activity: 86nmol phosphate incorporated into peptide substrate (ERMRPRKRQGSVRRRV) per minute per mg protein at 30°C for 15 minutes using a final concentration of 50μM ATP (0.83 uCi/assay).
• Species: Baculovirus
• Recombinant: Recombinant
• Protein Tag: GST
• Form: Liquid
• Purity or Quality Grade: ≥90% by SDS-PAGE