Gibco™ Human Prokineticin-2 Recombinant Protein, PeproTech®

Catalog No.	Quantity
10046100UG	100 μg
100-46-1MG	1 mg
100-46-20UG	20 μg
10046250UG	250 μg
10046500UG	500 μg
100-46-50UG	50 μg
100-46-5UG	5 μg

Catalog No. 10046100UG Supplier Gibco™ Supplier No. 10046100UG

Description

Recombinant Protein

Recombinant Human Prokineticin-2 is an 8.8 kDa protein consisting of 81 amino acid residues, including ten cysteine residues that can potentially form five pairs of intra-molecular disulfide bonds. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.

Specifications

• Accession Number: Q9HC23
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 60675
• Molecular Weight (g/mol): 8.8 kDa
• Name: Human Prokineticin-2
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: Bombina variegata 8 kD protein; Bombina variegata 8 kDa protein; Bv 8 homolog (Bombina variegata); BV8; Bv8/prokineticin 2-like protein; Bv8/prokineticin 2-like protein splice variant; HH4; homolog of mouse Bv8 (Bombina variegata 8 kDa); homolog of mouse Bv8 (Bombina variegata 8 kDa); prokineticin 2; KAL4; MIT1; PK2; Prok1; Prok2; prokineticin 1; prokineticin 2; prokineticin 2 beta; prokineticin-2; Protein Bv8 homolog; secreted protein
• Common Name: PROK2
• Gene Symbol: PROK2
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: AVITGACDKD SQCGGGMCCA VSIWVKSIRI CTPMGKLGDS CHPLTRKVPF FGRRMHHTCP CLPGLACLRT SFNRFICLAQ K
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.