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CPC Scientific Glp-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH (trifluoroacetate salt) 1MG
Supplier: CPC Scientific AMYD015B
The fibrils in the plaques formed in the brains of patients with Alzheimer?s disease contain significant amounts of truncated Abeta proteins. This fragments contain an N-terminal pyroglutamic acid. The g-carboxy group of glutamic acid forms a cyclic bond with the free N-terminal amino group to form pyroglutamateONE-LETTER SEQUENCE: Glp-FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVMOLECULAR FORMULA: CHNOSMOLECULAR WEIGHT:4125.68STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [161818-04-8], SYNONYMS: (Pyr)-Amyloid β-Protein (3-40) RESEARCH AREA: Alzheimer's DiseaseREFERENCES: Mok, SS. et al. J. Neurosci. Res. 61, 449 (2000); Russo, C. et al. Nature. 405, 531 (2000)
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