Gibco™ Human Relaxin-2 Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Human Relaxin-2 is a non-glycosylated, 6.0 kDa, disulfide-linked, heterodimeric protein consisting of a 24 amino acid A-chain, and a 29 amino acid B-chain. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Relaxin 1 (also referred to as Relaxin or RLXH1) is a peptide hormone produced by the corpora lutea of the ovary during pregnancy in many mammalian species, including human. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, Relaxin 1 may influence the timing of parturition. Like insulin, Relaxin 1 consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the amino-terminus. The gene that encodes the human Relaxin 1 protein maps to chromosome 9. Relaxin 2, a related protein, is selectively expressed in the ovary during pregnancy. The gene that encodes the human Relaxin 2 protein also maps to chromosome 9.

Specifications

• Accession Number: P04090
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 6019
• Molecular Weight (g/mol): 6 kDa
• Name: Human Relaxin-2
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: bA12D24.1.1; bA12D24.1.2; H2; H2-preprorelaxin; H2-RLX; Prorelaxin H2; relaxin 2; Relaxin A chain; Relaxin B chain; relaxin H2; relaxin, ovarian, of pregnancy; RLN2; RLX H2-RLX; RLXH2
• Common Name: Relaxin 2
• Gene Symbol: RLN2
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: A-Chain: QLYSALANKC CHVGCTKRSL ARFC B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.