Invitrogen™ Human SHISA4 Synthetic Peptide

Catalog No.	Quantity
PEP1571	50 μg

Catalog No. PEP1571 Supplier Invitrogen™ Supplier No. PEP1571

Description

Synthetic Peptide

SHISA4 Synthetic Peptide, PEP-1571, from Invitrogen.

SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.

Specifications

• Gene ID (Entrez): 149345
• Species: Human
• Purification Method: purified
• Accession Number: Q96DD7
• Common Name: Human SHISA4
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: SHISA4
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS