R&D Systems™ Human SP-D (NP_003010) VersaClone cDNA

Catalog No.
RDC2559	10 μg

Catalog No. RDC2559 Supplier R&D Systems™ Supplier No. RDC2559

Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

• SFTPD surfactant protein D [ Homo sapiens (human) ]
• Also known as: SP-D; PSP-D; SFTP4; COLEC7
• The SP-D insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
• A collectin family (of innate immune modulators) protein consisting of a collagen-like sequence followed by a C-type lectin domain.
• It is constitutively secreted by alveolar lining cells and epithelium associated with tubular structures.
• In addition, SP-D is produced by epithelial cells of the gastrointestinal tract and exocrine glands.
• SP-D binds to patterns of neutral sugars on micro-organisms to mediate direct opsonization and phagocytosis and is an important component of the innate immune system.
• SP-D is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. It may also be involved in surfactant metabolism.
• For reasearch use only. Not for use in humans.

Specifications

• Gene: hSFTPD
• Accession Number: NP_003010
• Concentration: 10 μg at 0.2 μg/μL
• Formulation: cDNA is provided in 10 mM Tris-Cl, pH 8.5
• Insert Type: 1141 bp
• Gene ID (Entrez): 6441
• Content And Storage: Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Species: Human
• Quantity: 10 μg