R&D Systems™ Human SR-AI/MSR (NP_619729) VersaClone cDNA

Catalog No.
RDC2580	10 μg

Catalog No. RDC2580 Supplier R&D Systems™ Supplier No. RDC2580

Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

• MSR1 macrophage scavenger receptor 1 [ Homo sapiens (human) ]
• Also known as: SRA; SR-A; CD204; SRAI; phSR1; phSR2; SCARA1; SR-AII; SRAIII
• The scavenger receptor (SR) family is a group of membrane receptors that share the common ability to bind and internalize modified forms of low-density lipoproteins (mLDL).
• The three SR-A alternatively spliced isoforms (I, II, and III) and a structurally similar protein, MARCO, make up the A class of homotrimeric, type II membrane proteins.
• SR-AI has an N-terminal cytoplasmic domain, transmembrane domain, spacer domain, a-helical coiled coil domain, collagen-like domain, and C-terminal cysteine-rich domain.
• SR-As are expressed by most tissue macrophages and dendritic cells.
• SR-As bind a broad range of polyanionic ligands and therefore have been implicated in many physiological and pathophysiological functions.
• The SR-AI/MSR insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
• For reasearch use only. Not for use in humans.

Specifications

• Gene: hMSR1
• Accession Number: NP_619729
• Concentration: 10 μg at 0.2 μg/μL
• Formulation: cDNA is provided in 10 mM Tris-Cl, pH 8.5
• Insert Type: 1369 bp
• Gene ID (Entrez): 4481
• Content And Storage: Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Species: Human
• Quantity: 10 μg