Invitrogen™ Human STIM1 Synthetic Peptide

Catalog No.	Quantity
PEP0488	50 μg

Catalog No. PEP0488 Supplier Invitrogen™ Supplier No. PEP0488

Description

Synthetic Peptide

STIM1 Synthetic Peptide, PEP-0488, from Invitrogen.

STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.

Specifications

• Gene ID (Entrez): 6786
• Species: Human
• Purification Method: purified
• Accession Number: Q13586
• Common Name: Human STIM1
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: STIM1
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS