Abnova™ Human TARDBP Full-length ORF (NP_031401.1, 1 a.a. - 414 a.a.) Recombinant Protein with GST-tag at N-terminal

Liquid

Supplier:  Abnova™ H00023435P02S

Catalog No. 89-964-076

Description

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]

Sequence: MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM

Specifications

• Accession Number: NP_031401.1
• Gene ID (Entrez): 23435
• Name: Human TARDBP Full-length ORF (NP_031401.1, 1 a.a. - 414 a.a.) Recombinant Protein with GST-tag at N-terminal
• Quality Control Testing: 12.5% SDS-PAGE Stained with Coomassie Blue
• Storage Requirements: Store at −80°C. Aliquot to avoid repeated freezing and thawing.
• Gene Alias: ALS10, TDP-43
• Gene Symbol: TARDBP
• Recombinant: Recombinant
• Expression System: wheat germ expression system

• Formulation: 50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Weight (g/mol): 71.1kDa
• Purification Method: Glutathione Sepharose 4 Fast Flow
• Quantity: 10μg
• Regulatory Status: RUO
• Common Name: TARDBP
• Species: Wheat Germ (in vitro)
• Protein Tag: GST Tag
• Form: Liquid