Abnova™ Human TGFB1 (NP_004603.1, 200 a.a. - 503 a.a.) Partial Recombinant Protein with GST-tag expressed in Baculovirus infected Sf21 cells

Catalog No.	Quantity
89-964-533	5 μg

Catalog No. 89-964-533 Supplier Abnova™ Supplier No. P5804

Description

Used for Func, SDS-PAGE

TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM]

Specifications

• Accession Number: NP_004603.1
• For Use With (Application): Functional Study, SDS-PAGE
• Formulation: Liquid
• Gene ID (Entrez): 7040
• Molecular Weight (g/mol): 61kDa
• Name: TGFB1 (Human) Recombinant Protein
• Preparation Method: Baculovirus infected insect cell (Sf21) expression system
• Purification Method: Glutathione sepharose chromatography
• Quality Control Testing: SDS-PAGE Stained with Coomassie Blue
• Quantity: 5 μg
• Storage Requirements: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Regulatory Status: RUO
• Gene Alias: CED/DPD1/TGFB/TGFbeta
• Common Name: TGFB1
• Gene Symbol: TGFB1
• Biological Activity: The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip3000.
  Substrate : TopoIIa peptide. ATP: 100 μM.
• Species: Baculovirus
• Recombinant: Recombinant
• Protein Tag: GST
• Expression System: Baculovirus infected insect cell (Sf21) expression system
• Form: Liquid
• Purity or Quality Grade: 74% by SDS-PAGE/CBB staining