Gibco™ Human TMIGD2/CD28H Fc Recombinant Protein, PeproTech®

Catalog No.	Quantity
31042500UG	500 μg
31042100UG	100 μg
310-42-10UG	10 μg
310-42-1MG	1 mg
31042250UG	250 μg
310-42-50UG	50 μg

Catalog No. 31042500UG Supplier Gibco™ Supplier No. 31042500UG

Description

Recombinant Protein

CHO cell-derived Recombinant Human TMGID2/CD28H Fc is a glycosylated, disulfide-linked homodimer of 361-amino-acid-residues whose monomer consists of the 128-amino-acid extracellular domain fused to the 231-amino-acid length Fc portion of human IgG1 by two glycine residues. The calculated molecular weight of monomeric Recombinant TMIGD2/CD28H Fc is 40.1kDa; however, due to glycosylation, it migrates at an apparent molecular weight of approximately 55-60 kDa by SDS-PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

TMIGD2 (transmembrane and immunoglobulin domain containing 1), also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1), is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins. TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration.

Specifications

• Accession Number: Q96BF3
• For Use With (Application): ELISA, Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 126259
• Molecular Weight (g/mol): 40.1 kDa
• Name: Human TMIGD2/CD28H Fc
• Quantity: 500 μg
• Source: CHO cells
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: CD28 homolog; CD28 homologue; CD28H; IGPR1; IGPR-1; Immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor-1; TMIGD2; transmembrane and immunoglobulin domain containing 2; transmembrane and immunoglobulin domain-containing protein 2; transmembrane and immunoglobulin domain-containing protein 2 variant 2; transmembrane and immunoglobulin domain-containing protein 2 variant 3; UNQ3059/PRO9879
• Common Name: TMIGD2
• Gene Symbol: TMIGD2
• Biological Activity: Determined by its ability to bind recombinant human B7-H7 protein in a functional ELISA.
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: Fc-tag
• Sequence: LSVQQGPNLL QVRQGSQATL VCQVDQATAW ERLRVKWTKD GAILCQPYIT NGSLSLGVCG PQGRLSWQAP SHLTLQLDPV SLNHSGAYVC WAAVEIPELE EAEGNITRLF VDPDDPTQNR NRIASFPGGG PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
• Content And Storage: -20°C
• Expression System: CHO cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.