Invitrogen™ Human TOLLIP Synthetic Peptide

Catalog No.	Quantity
PEP0345	50 μg

Catalog No. PEP0345 Supplier Invitrogen™ Supplier No. PEP0345

Description

Synthetic Peptide

TOLLIP Synthetic Peptide, PEP-0345, from Invitrogen.

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.

Specifications

• Gene ID (Entrez): 54472
• Species: Human
• Purification Method: purified
• Accession Number: Q9H0E2
• Common Name: Human TOLLIP
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: TOLLIP
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS