Invitrogen™ Human TOX Synthetic Peptide

Catalog No.	Quantity
PEP1465	50 μg

Catalog No. PEP1465 Supplier Invitrogen™ Supplier No. PEP1465

Description

Synthetic Peptide

TOX Synthetic Peptide, PEP-1465, from Invitrogen.

TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.

Specifications

• Gene ID (Entrez): 9760
• Species: Human
• Purification Method: purified
• Accession Number: O94900
• Common Name: Human TOX
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: TOX
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS