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ACROBiosystems Human TrkB 2Vials

Supplier:  ACROBiosystems CHEKATP0822VIALS

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Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2 / TrkB contains two Ig-like C2-type (immunoglobulin-like) domains two LRR (leucine-rich) repeats one LRRCT domain one LRRNT domain one protein kinase domain. NTRK2 / Trk-B is expressed in the central and peripheral nervous system. The catalytic activity of NTRK2 is “ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate”. NTRK2 / TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival proliferation migration differentiation and synapse formation and plasticity.

Catalog No. 50-253-5288


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