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Gibco™ Human VEGF-C Recombinant Protein, PeproTech®

Catalog No. 10020CD1MG
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Catalog No. Quantity
10020CD1MG 1 mg
10020CD100 100 μg
10020CD20UG 20 μg
10020CD250 250 μg
10020CD500 500 μg
10020CD5UG 5 μg
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Catalog No. 10020CD1MG Supplier Gibco™ Supplier No. 10020CD1MG
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Description

Recombinant Protein

Recombinant Human VEGF-C is a disulfide-linked homodimeric protein consisting of two 13.5 kDa polypeptide chains of 116 amino acid residues. Due to glycosylation, the protein migrates as a 30.0-33.0 kDa band by SDS-PAGE analysis under non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P49767
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 7424
Molecular Weight (g/mol) 26.2 kDa
Name Human VEGF-C
Quantity 1 mg
Source HEK293 cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias AW228853; Flt4 ligand; FLT4 ligand DHM; Flt4-L; LMPH1D; Vascular endothelial growth factor C; vascular endothelial growth factor C isoform 129; vascular endothelial growth factor C isoform 184; vascular endothelial growth factor-related protein; VEGF3; VEGFC; VEGF-C; VRP
Common Name VEGFC
Gene Symbol VEGFC
Biological Activity Determined by its ability to stimulate the proliferation of human microvascular endothelial cells (HMVEC) in low serum conditions.
Conjugate Unconjugated
Recombinant Recombinant
Sequence AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGVATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTSYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR
Content And Storage -20°C
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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