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Invitrogen™ VEGF Receptor 2/KDR Human ELISA Kit Non-distribution product as customer accommodation.

For the quantitative detection of human VEGF-R2/KDR.

Manufacturer:  Invitrogen™ BMS2019TEN

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Catalog No. 50-178-89


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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human VEGF-R2/KDR
Biotin-Conjugate anti-human VEGF-R2/KDR monoclonal antibody
Streptavidin-HRP
Human VEGF-R2/KDR Standard lyophilized, 10ng/mL upon reconstitution
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. VEGF are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGF Receptor 1 and VEGF Receptor 2 are both expressed in an endothelial cell-specific manner. They are detectable in virtually all tissues in adults and embryos. Monocytes express VEGF Receptor 1 and VEGF Receptor 2. VEGF Receptor 2 is involved in commitment of endothelial-cell lineages and to cell proliferation, while VEGF Receptor 1 seems to be responsible for guiding endothelial cells into the proper spatial organization of the lumen-containing vessels. VEGF Receptor 2 binds VEGF with high affinity but does not bind PIGF. The signalling and trafficking of this VEGF receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, and T-cell protein tyrosine phosphatase. Mutations of VEGF are implicated in infantile capillary hemangiomas.
Specifications

Specifications

P35968
Biotin
3791
ELISA Kit
7.0 pg/mL
Plasma, 20 μL|Serum, 20 μL|Supernatant, 20 μL
1 hr. 20 min.
Human
KDR, FLK1, Kinase insert domain receptor, CD309
5.3%
Human
HRP
78-5,000 pg/mL
ELISA
Adhesive Plate Covers
RUO
50 μL (1:25 prediluted)
2°C to 8°C
3 hr. 30 min.
CD309,FLK1,VEGFR,VEGFR2
9.8%
10 x 96 Tests
Plasma, Serum, Supernatant
Colorimetric Microplate Reader
SDS
Documents
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