Invitrogen™ Human VKORC1 Synthetic Peptide

Catalog No.	Quantity
PEP1401	50 μg

Catalog No. PEP1401 Supplier Invitrogen™ Supplier No. PEP1401

Description

Synthetic Peptide

VKORC1 Synthetic Peptide, PEP-1401, from Invitrogen.

Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.

Specifications

• Gene ID (Entrez): 79001
• Species: Human
• Purification Method: purified
• Accession Number: Q9BQB6
• Common Name: Human VKORC1
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: VKORC1
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS