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Invitrogen™ Human VPS53 Synthetic Peptide

Catalog No. PEP0669
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50 μg
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Catalog No. Quantity
PEP0669 50 μg
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Catalog No. PEP0669 Supplier Invitrogen™ Supplier No. PEP0669
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Description

Synthetic Peptide

VPS53 Synthetic Peptide, PEP-0669, from Invitrogen.

The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 55275
Species Human
Purification Method purified
Accession Number Q5VIR6
Common Name Human VPS53
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol VPS53
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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