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Invitrogen™ HVCN1 Polyclonal Antibody
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Catalog No. PIPA521008
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100 μg
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Catalog No. Quantity
PIPA521008 100 μg
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Catalog No. PIPA521008 Supplier Invitrogen™ Supplier No. PA521008
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human spleen tissue lysate. PA5-21008 can be used with blocking peptide PEP-1122.

HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HVCN1
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene HVCN1
Gene Accession No. Q3U2S8, Q96D96
Gene Alias 0610039P13Rik; AI450555; BTS; HV1; Hvcn1; hydrogen voltage gated channel 1; hydrogen voltage-gated channel 1; mVSOP; RGD1310788; UNQ578/PRO1140; Voltage sensor domain-only protein; voltage-gated hydrogen channel 1; Vsop; Vsop.
Gene Symbols HVCN1
Host Species Rabbit
Immunogen A 17 amino acid peptide near the carboxy terminus of human HVCN1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 304485, 74096, 84329
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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