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Genscript Corporation GRO beta/CXCL2 Human

Supplier:  Genscript Corporation Z0330425

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Human GRO- GRO- (MIP-2 ) and GRO- (MIP-2 ) are products of three distinct nonallelichuman genes GRO- and GRO- share 90% and 86% amino acid sequence homology respectively with GRO All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators such as IL-1 and TNF in monocytes fibroblasts melanocytes and epithelial cells In certain tumor cell lines GRO is expressed constitutively Similar to other alpha chemokines the three GRO proteins are potent neutrophil attractants and activators In addition these chemokines are also active toward basophils

Catalog No. 50-000-59396


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