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HVEM/TNFRSF14 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

$395.30

Specifications

Antigen HVEM/TNFRSF14
Concentration 0.27 mg/mL
Applications Immunohistochemistry (Paraffin)
Conjugate Unconjugated
Format Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-6053
Encompass_Preferred
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Proteintech Group IncSupplier Diversity Partner
101381AP150UL
150 μL
Each for $395.30
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Description

Description

TNFRSF14 is a member of the TNF-receptor superfamily. TNFRSF14 was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to TNFRSF14 has been shown to be part of the viral entry mechanism. The cytoplasmic region of TNFRSF14 was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. Activation of the signal transduction pathway involving TNFRSF14 in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these TNFRSF14 variants have not been determined.
Specifications

Specifications

HVEM/TNFRSF14
Immunohistochemistry (Paraffin)
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Polyclonal
-20°C
0.27 mg/mL
Unconjugated
Rabbit
Human
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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