The use of SPE sample preparation can significantly enhance the robustness and reliability of many biological, pharmaceutical, forensic and environmental applications.
Thermo Scientific™ HyperSep Hypercarb SPE Cartridges feature a unique graphite carbon-based material that retains highly polar compounds where silica and resin columns fail. The chemistry allows selectivity for structurally similar compounds, and allows the separation of compounds using simple solvents.
HyperSep Hypercarb SPE Cartridges are packed with 30µm spherical particles of 100% porous graphitic carbon (PGC). Composed of flat sheets of hexagonally arranged carbon atoms with a fully satisfied valence, the surface of Hypercarb is crystalline and highly reproducible, with no micropores.
The chemistry is pH stable 0 to 14, and offers a unique retention mechanism that provides completely different selectivity than silica or polymeric phases, determined by the strength of interaction between analytes and the Hypercarb surface.
High batch-to-batch reproducibility ensures consistent, reproducible analytical performance
Strong retention properties allow use of low bed weights for concentrated extracts
No restriction for polar compounds
No restriction on eluents—use 100% organic or 100% aqueous and anything in between
HyperSep SPE Cartridges and Plates
Thermo Scientific™ HyperSep™ solid phase extraction cartridges offer reproducible, reliable sample preparation in a traditional format. Available in a wide range of chemistries and bed weights, the cartridges are ideal for large samples and conform to industry standard configurations, allowing efficient routine processing by vacuum, by positive pressure or centrifugation.
The Thermo Scientific™ HyperSep-96™ system incorporates traditional solid phase extraction sorbents into 96-well plate format providing fast analysis without sacrificing accuracy or reproducibility. The innovative design of HyperSep-96 well plates provides flexibility for both method development and scale adjustment to 96-well without method revalidation. Well plates are customizable, allowing any arrangement of wells with differing sorbent chemistries for simultaneous processing. HyperSep-96 products are either available in packs of 100 individual wells or in pre-assembled plates.
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