DescriptionmiRNA inhibitors are small, chemically modified single-stranded RNA molecules designed to specifically bind to and inhibit endogenous miRNA molecules and enable miRNA functional analysis by down-regulation of miRNA activity.
We have now released the second generation of miRNA inhibitors,mirVana miRNA Inhibitors which:
- Display better potency than lead competitor's product
- Offer maximum and consistent effect in vitro at low miRNA inhibitor concentration
- Are non toxic
- Target the most updated Sanger content
- Can be used in vitro and in vivo, offering consistency throughout your entire research project
Positive and negative controls are also available for use along with mirVana miRNA Inhibitors in miRNA down-regulation experiments.
mirVana miRNA Inhibitor Negative Control #1
mirVana miRNA Inhibitor Negative Control #1 is intended for use as a negative control for experiments using mirVana miRNA Inhibitors. Transfect this negative control using the same methodology as for your positive control (such as let-7c Positive Control) and experimental mirVana miRNA Inhibitors. Use target expression from negative control-transfected samples as a baseline for evaluation of the effect of the control and experimental miRNA inhibitor on target gene expression.
First Generation Inhibitor Controls
Our first-generation miRNA inhibitors (and controls), Ambion Anti-miR miRNA Inhibitors, have lower specificity and potency, plus a lower strand specificity compared to the new mirVana miRNA Inhibitors. These first-generation inhibitors are recommended for completing ongoing in vitro miRNA studies. For new studies or in vivo studies, we highly recommend our new mirVana miRNA Inhibitors and their corresponding controls.
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|miRNA and non-coding RNA analysis|
For Research Use Only. Not for use in diagnostic procedures.
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