DescriptionAmbion Silencer SelectNegative Control #2 siRNA is extensively validated and an ideal control for many aspects of an siRNA experiment.
- Premium-quality siRNA, highly purified and ready to use
- Functionally proven to have minimal effects on cell proliferation and viability
- Include Silencer Select modifications for enhanced specificity
- For use in human, mouse, and rat cells
What are Silencer Select siRNAs?
Silencer Select siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemical modifications, to yield siRNAs with unrivalled efficacy, potency, and specificity. The result is fewer failed experiments due to poor silencing, and cleaner, more consistent phenotypic data.
Silencer Select Negative Control #2 siRNA:
Negative control siRNAssiRNAs with sequences that do not target any gene productare essential for determining the effects of siRNA delivery and for providing a baseline to compare siRNA-treated samples. Silencer Select Negative Control #2 siRNA has been carefully designed and extensively tested, and has no significant sequence similarity to mouse, rat, or human gene sequences. This negative control siRNA has been tested by microarray analysis and shown to have minimal effects on gene expression. It has also been tested in multi-parametric, cell-based assays and shown to have no significant effect on cell proliferation, viability, or morphology in the cell lines tested.
Silencer Select siRNAs are manufactured in a state-of-the-art facility under the highest quality standards. Rigorous quality control procedures include MALDI-TOF mass spectrometry analysis and analytical HPLC to monitor purity. Each siRNA is also assessed by gel electrophoresis to confirm that the strands anneal properly.
Accessory Product: siPORT NeoFX Transfection Agent (SKU #AM4510 and #AM4511)
siPORT NeoFX Transfection Agent is a versatile, lipid-based transfection agent for the efficient transfection of siRNA into cultured cells. The protocol can be adapted to a wide range of cells and experimental designs, including high-throughput applications. Silencer Select siRNA controls have specific chemical modifications; they are designed to be used with Silencer Select siRNAs. If you are using other siRNA products, such as BLOCK-iT siRNAs, Ambion Silencer siRNAs, or STEALTH RNAi siRNAs, we recommend that you use control siRNAs designed for use with those siRNAs for more reliable experimental results.
|Cell culture, transfection, RNAi transfection, synthetic siRNA transfection, RNAi, epigenetics and non-coding RNA research, RNAi, siRNA|
|siRNA, nuclease-free Water (1.75mL)|
For Research Use Only. Not for use in diagnostic procedures.
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