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Invitrogen™ IARS2 Polyclonal Antibody
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Catalog No. PIPA555015
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100 μL
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PIPA555015 100 μL
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Catalog No. PIPA555015 Supplier Invitrogen™ Supplier No. PA555015
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NVIHPDVVVN GGQDQSKEPP YGADVLRWWV ADSNVFTEVA IGPSVLNAAR DDISKLRNTL RFLLGNVADF NPETDSIPVN DMYV Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 77%.

The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IARS2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IARS2
Gene Accession No. Q9NSE4
Gene Alias 2010002H18Rik; C79125; CAGSSS; EC 6.1.1.5; Iars2; IleRS; isoleucine tRNA ligase 2, mitochondrial; isoleucine--tRNA ligase, mitochondrial; isoleucine-tRNA synthetase 2, mitochondrial; Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 2, mitochondrial; isoleucyl-tRNA synthetase, mitochondrial; mitochondrial isoleucine tRNA synthetase; RGD1311857
Gene Symbols IARS2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IARS2. Recombinant protein control fragment (Product #RP-94009).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55699
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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