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IARS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501731416 Shop All Proteintech Group Inc Products
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50-173-1416 150 μL
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Catalog No. 50-173-1416 Supplier Proteintech Group Inc Supplier No. 171701AP150UL
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Description

Rabbit Polyclonal Antibody

The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.

Specifications

Antigen IARS2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IARS2
Gene Accession No. Q8BIJ6, Q9NSE4
Gene Alias IARS2, IleRS, Isoleucine tRNA ligase
Gene Symbols Iars2
Host Species Rabbit
Immunogen IARS2 Fusion Protein Ag10696
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 364070, 381314, 55699
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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