ICAM-1 Mouse anti-Human, Clone: 2F9A8, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 602991IG150UL

Catalog No. 50-173-6394

Description

Intercellular adhesion molecule-1 (ICAM-1, CD54) is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for lymphocyte function-associated (LFA) antigens, a beta 2 leukocyte integrin. The normal function of human ICAM-1 is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). It is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. ICAM-1 has a tissue distribution similar to that of the major histocompatibility complex class II antigens and is likely to play a role in inflammatory responses.

Specifications

• Antigen: ICAM-1
• Classification: Monoclonal
• Concentration: 0.7 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P05362
• Gene Symbols: ICAM1
• Immunogen: ICAM-1 Fusion Protein Ag8309
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 2F9A8
• Conjugate: Unconjugated
• Gene: ICAM1
• Gene Alias: BB2, CD54, ICAM 1, ICAM1, ICAM-1, P3.58
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3383
• Content And Storage: -20°C
• Form: Liquid