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ICAM-1 Mouse anti-Human, Clone: 2F9A8, Proteintech
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Catalog No. 501736394 Shop All Proteintech Group Inc Products
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50-173-6394 150 μL
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Catalog No. 50-173-6394 Supplier Proteintech Group Inc Supplier No. 602991IG150UL
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Mouse Monoclonal Antibody

Intercellular adhesion molecule-1 (ICAM-1, CD54) is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for lymphocyte function-associated (LFA) antigens, a beta 2 leukocyte integrin. The normal function of human ICAM-1 is to provide adhesion between endothelial cells and leukocytes after injury or stress. ICAM-1 binds to leukocyte function-associated antigen (LFA-1) or macrophage-1 antigen (Mac-1). It is found on leukocytes, fibroblasts, epithelial cells and endothelial cells and its expression is regulated by inflammatory cytokines. ICAM-1 has a tissue distribution similar to that of the major histocompatibility complex class II antigens and is likely to play a role in inflammatory responses.

Specifications

Antigen ICAM-1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2F9A8
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ICAM1
Gene Accession No. P05362
Gene Alias BB2, CD54, ICAM 1, ICAM1, ICAM-1, P3.58
Gene Symbols ICAM1
Host Species Mouse
Immunogen ICAM-1 Fusion Protein Ag8309
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3383
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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