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Invitrogen™ ICAM-3 Monoclonal Antibody (ICO-60)

Catalog No. 01670390
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100 μg
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Catalog No. Quantity
01-670-390 100 μg
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Catalog No. 01-670-390 Supplier Invitrogen™ Supplier No. MA17656
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Description

Mouse Monoclonal Antibody

MA1-7656 detects ICAM-3 from human samples. MA1-7656 has been successfully used in flow cytometry procedures. The MA1-7656 immunogen is Leukocytes.

CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ICAM-3
Applications Flow Cytometry
Classification Monoclonal
Clone ICO-60
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin, 0.5% saccharose and 0.01% sodium azide; pH 7.2
Gene ICAM3
Gene Accession No. P32942
Gene Alias CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3
Gene Symbols ICAM3
Host Species Mouse
Immunogen Leukocytes.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3385
Target Species Human
Content And Storage 4°C short term, -80°C long term
Product Type Antibody
Form Liquid
Isotype IgG1
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