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Invitrogen™ ICOS (CD278) Monoclonal Antibody (SP98)
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Catalog No. PIMA516415 Shop All Thermo Scientific Products
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500 μL
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PIMA516415 500 μL
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Catalog No. PIMA516415 Supplier Invitrogen™ Supplier No. MA516415
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Description

Rabbit Monoclonal Antibody

Heat-mediated antigen retrieval is recommended prior to staining, using a 1mM EDTA buffer, pH 8.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil or reactive lymph node tissue.

ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ICOS (CD278)
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SP98
Concentration Conc. not determined
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene ICOS
Gene Accession No. Q9Y6W8
Gene Alias Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115
Gene Symbols ICOS
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the C-terminus of human CD278.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29851
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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