Iduronate 2 sulfatase Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1A3F9, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 661121IG150UL

Catalog No. 50-173-6548

Description

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Specifications

• Antigen: Iduronate 2 sulfatase
• Classification: Monoclonal
• Concentration: 0.52 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P22304, Q08890
• Gene Symbols: IDS
• Immunogen: Iduronate 2 sulfatase Fusion Protein Ag19095
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Pig, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 1A3F9
• Conjugate: Unconjugated
• Gene: IDS
• Gene Alias: IDS, iduronate 2 sulfatase, Idursulfase
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100512880, 15931, 3423, 363513
• Content And Storage: -20°C
• Form: Liquid