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Invitrogen™ Iduronate 2 Sulfatase Polyclonal Antibody
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Catalog No. PIPA579439
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100 μg
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Catalog No. Quantity
PIPA579439 100 μg
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Catalog No. PIPA579439 Supplier Invitrogen™ Supplier No. PA579439
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HELA Cell, SMMC Cell, A549 Cell, MCF-7 Cell, COLO Cell. IHC: Human Placenta Tissue.

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Iduronate 2 Sulfatase
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene Ids
Gene Accession No. P22304
Gene Alias alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; idursulfase; MPS2; SIDS
Gene Symbols Ids
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase (430-448aa ELCREGKNLLKHFRFRDLE).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3423
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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