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Invitrogen™ IFITM2 Polyclonal Antibody
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Catalog No. PIPA590244
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100 μL
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PIPA590244 100 μL
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Catalog No. PIPA590244 Supplier Invitrogen™ Supplier No. PA590244
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MNHIVQTFSP VNSGQPPNYE MLKEEQEVAM LGVPHNPAPP MSTVIHIRSE TSVPDHVVWS LFNTLFMNTC CLGFIAFAYS VKSRDRKMVG DVTGAQAYAS; Positive Samples: HeLa; Cellular Location: Cell membrane, Single-pass membrane protein.

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFITM2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene IFITM2
Gene Accession No. Q01629
Gene Alias 1-8D; dispanin subfamily A member 2c; DSPA2c; IFITM2; ifm2; interferon induced transmembrane protein 2; interferon-induced transmembrane protein 2; Interferon-inducible protein 1-8D
Gene Symbols IFITM2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFITM2 (NP_0064262).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10581
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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