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Invitrogen™ IFN beta Polyclonal Antibody
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Catalog No. PIPA520390
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100 μg
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Catalog No. Quantity
PIPA520390 100 μg
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Catalog No. PIPA520390 Supplier Invitrogen™ Supplier No. PA520390
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Description

Rabbit Polyclonal Antibody

A suggested positive control is A-20 cell lysate. PA5-20390 can be used with blocking peptide PEP-0507.

Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
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Specifications

Antigen IFN beta
Applications Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Ifnb1
Gene Accession No. P01574, P01575
Gene Alias Fibroblast interferon; Ifb; IFF; IFN b; IFN β; IFNB; Ifnb1; IFNbeta; IFN-beta; IFNβ; Interferon; Interferon b; Interferon beta; interferon beta 1; interferon beta 1, fibroblast; interferon beta protein; interferon, beta 1; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1
Gene Symbols Ifnb1
Host Species Rabbit
Immunogen A 17 amino acid peptide from near the center of human IFN-b.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15977, 3456
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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