IFN-γ Rat anti-Murine, Brilliant Ultraviolet 737, Clone: XMG1.2, BD Horizon
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 612769
The XMG1.2 monoclonal antibody specifically binds to mouse interferon- γ(IFN- γ) protein. IFN- γis a pleiotropic cytokine, of approximately 15-17 kDa, involved in the regulation of inflammatory and immune responses. It plays an important role in activation, growth, and differentiation of T and B lymphocytes, macrophages, NK cells and other non-hematopoietic cell types. IFN- γproduction is associated with the Th1 cell differentiation. The purified form of this antibody has been reported to be a neutralizing antibody.
Due to spectral differences between labeled cells and beads, using BD CompBeads can result in incorrect spillover values when used with BD Horizon BUV737 reagents. Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended. Different BUV737 reagents (e.g., CD4 vs. CD45) can have slightly different fluorescence spillover therefore, it may also be necessary to use clone specific compensation controls when using these reagents.
|Brilliant Ultraviolet 737|
|Mouse IFN-γ Recombinant Protein|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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